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Levels of serum anti-HBsAg IgG subclass elicited in mice immunized with different formulations of the hepatitis B vaccine. Values are expressed as mean of antibody level from 3 independent experiments ± standard variation. P < 0.05 (AlChS versus unadjuvanted group) in levels of IgG1; P ≤ 0.05 (S versus AlCh group), P < 0.01 (AlChS versus AlCh group), and P < 0.05 (AlChS versus AlS group) levels of IgG2b.
