Table 1.
Characteristics of patients.
| Patient characteristics | n = 395 |
|---|---|
| APACHE II score | 24 ± 7.8 |
|
| |
| Serum procalcitonin | 3.9 (IQR 25% 1.1, 75% 18.4) |
|
| |
| Admission during working hours | 147 (37%) |
| Admission after working hours | 248 (63%) |
|
| |
| Vasopressors at 72 hours | 236 (60%) |
|
| |
| Comorbid illnesses | |
| Malignancy | 86 (22%) |
| Metastatic cancer | 26 (7%) |
| Hematologic malignancy | 35 (9%) |
| Acute respiratory failure | 67 (17%) |
| Chronic renal failure | 64 (16%) |
| Dialysis dependent | 42 (11%) |
| Cirrhosis | 62 (16%) |
| Chronic diseases∗ | 235 (59%) |
|
| |
| No microbial growth on admission cultures | 200 (51%) |
|
| |
| Source of sepsis | |
| BSI | 83 (42%) |
| Respiratory | 72 (37%) |
| Urinary tract | 27 (14%) |
| Peritonitis | 11 (5%) |
| Surgical site | 10 (5%) |
|
| |
| Multidrug resistant organisms | 41 (21%) |
|
| |
| Fungal organisms | 36 (18%) |
|
| |
| Initial antimicrobial therapy appropriate | 112 (57%) |
|
| |
| ICU length of stay (days) | 6 (IQR 39) |
|
| |
| ICU mortality | 74 (18.7%) |
|
| |
| 28-day mortality | 114 (28.9%) |
∗ refers to chronic medical illnesses, that is, type 2 diabetes mellitus, coronary artery disease, and hypertension.