Table 2.
Correlation of ADAMTS8 mRNA expression and clinicopathological characteristics of gastric cancer samples.
| Variable | Patients (n) | ADAMTS8 expression relative to GAPDH | P value |
|---|---|---|---|
| Age (years) | |||
| <65 | 40 | 0.290 ± 0.102 | |
| ≥65 | 26 | 0.267 ± 0.115 | 0.405 |
| Gender | |||
| Male | 45 | 0.285 ± 0.112 | |
| Female | 21 | 0.273 ± 0.099 | 0.674 |
| Tumor differentiation | |||
| Well/moderate | 33 | 0.267 ± 0.111 | |
| Poor | 33 | 0.295 ± 0.103 | 0.289 |
| Invasive depth | |||
| T1 + T2 | 22 | 0.329 ± 0.101 | |
| T3 + T4 | 44 | 0.257 ± 0.103 | 0.009a |
| Tumor location | |||
| Upper + middle | 13 | 0.300 ± 0.110 | |
| Lower | 53 | 0.276 ± 0.107 | 0.481 |
| Size (cm) | |||
| <3 | 28 | 0.287 ± 0.128 | |
| ≥3 | 38 | 0.277 ± 0.091 | 0.713 |
| Lymph node metastasis | |||
| No | 20 | 0.402 ± 0.064 | |
| Yes | 46 | 0.229 ± 0.075 | <0.001a |
a P < 0.05; ADAMTS8: ADAM metallopeptidase with thrombospondin type 8 motif.