Change of beating rate of hiPS-CMs in response to
administration of CA4DP, CA4, or vehicle. A: Change of beating rate in response to
administration of CA4DP or vehicle (0.1% H2O). The beating rate of
hiPS-CMs was increased at 3 hours and 12 hours after administration of CA4DP. B:
Change of beating rate in response to administration of CA4 or vehicle (0.1% DMSO).
The beating rate of hiPS-CMs was increased at 15 minutes, 3 hours, and 12 hours
after administration of CA4. A, B: Each dot represents a mean ± SD.
*p<0.05 compared with hiPS-CMs given vehicle;
**p<0.01 compared with hiPS-CMs given
vehicle.