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. 2016 Jun 1;10(6):OE01–OE09. doi: 10.7860/JCDR/2016/19032.8054

[Table/Fig-2]:

[Table/Fig-2]:

A 50-year-old man had symptoms of sensori-motor neuropathy for past 8 months and altered sensorium for past 7 days. He had history of daily metronidazole intake for past 18 months & 1 week back, dose was increased to 2 gm/day. (a) T2W MRI shows splenium hyperintensity in axial (white thin arrow) and sagittal (black thin arrow) views. DWI and ADC maps show diffusion restriction & low ADC (black thick arrow), respectively, in the corresponding areas of corpus callosum. (b) Follow-up MRI 3 weeks after drug withdrawal shows complete resolution of lesions, and the patient also recovered of encephalopathy.