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. 2016 Jun 30;8(7):199. doi: 10.3390/toxins8070199

Figure 1.

Figure 1

Selected phytochemicals that target signaling pathways involved in stemness maintenance and survival of CSCs. PTCH: Patched, receptors for hedgehog; FZD: Frizzled, receptors for Wnt; Dsh: disheveled, a downstream molecule of FZD; NICD: Notch intracellular domain, a Notch fragment cleaved by γ-secretase; RTKs: receptor tyrosine kinases; GFs: growth factors.