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. 2016 Jul 12;8(7):216. doi: 10.3390/toxins8070216

Figure 1.

Figure 1

Scheme of the genomic organization of pre-pro EOC00006-like PII-SVMP (A) and pre-pro EOC00028-like PI-SVMP (B) genes. The distribution, phase, and size of the 14 (PII) and 12 (PI) introns and the boundaries of the protein-coding regions are highlighted. SP, signal peptide. Homologous exons and introns have identical numbering. Intron 12 of the PI-SVMP gene corresponds to the fusion of the genomic segment spanning intron12*-exon13*-intron13*. Mature PII- and PI-SVMP amino acid sequences span 299 and 263 amino acid residues, respectively. Zn2+, relative location of the catalytic Zn2+-binding environment; RGD, integrin-binding arginine-glycine-aspartic acid tripeptide motif.