Table 2.
Presence (%) of increased gastrointestinal symptomsa in untreated, short-term (GFD 1–2 years) treated and long-term (GFD ≥ 3 years) treated celiac disease patients and in healthy controls.
| Celiac Patients on a GFD n = 728 | ||||
|---|---|---|---|---|
| GSRS Score | Untreated Patients n = 128 | Short Treatment n = 93 | Long Treatment n = 635 | Non-Celiac Controls n = 160 |
| Total score | 48 b | 27 c | 23 c | 16 |
| Indigestion | 41 b | 18 | 17 | 14 |
| Diarrhea | 47 b | 32 c,d | 21 | 15 |
| Abdominal pain | 43 b | 20 | 18 | 14 |
| Reflux | 34 b | 20 c | 19 c | 11 |
| Constipation | 16 | 18 | 18 | 16 |
GSRS, Gastrointestinal Symptom Rating Scale; GFD, gluten-free diet. a Defined as GSRS scores > 1 SD compared to mean values of healthy controls; b p < 0.05 compared with short and long treatment groups and with controls; c p < 0.05 compared with healthy controls; d p < 0.05 compared with long treatment group.