Table 1.
Correlation between tumor multifocality and clinicopathological features in PTMCs
| Clinicopathological feature (n = 383) | Multifocal PTMC (n = 103, 26.9%) | Unifocal PTMC (n = 280, 73.1%) | p-value |
|---|---|---|---|
| Age (yr) | |||
| < 45 | 43 (41.7) | 144 (51.4) | .093 |
| ≥ 45 | 60 (58.3) | 136 (48.6) | |
| Gender | |||
| Male | 18 (17.5) | 61 (21.8) | .355 |
| Female | 85 (82.5) | 219 (78.2) | |
| Tumor size (cm) | 0.67 ± 0.19 | 0.64 ± 0.20 | .389 |
| Total thyroidectomy | 83 (80.6) | 154 (55.0) | < .001 |
| Lobectomy | 20 (19.4) | 126 (45.0) | |
| Extrathyroidal extension | |||
| Present | 54 (52.4) | 125 (44.6) | .176 |
| Absent | 49 (47.6) | 155 (55.4) | |
| Lymph node metastasis | |||
| Present | 52 (50.5) | 95 (33.9) | .003 |
| Absent | 51 (49.5) | 185 (66.1) | |
| Tumor stage | |||
| I | 52 (50.5) | 203 (72.5) | < .001 |
| II | 0 | 0 | |
| III | 51 (49.5) | 75 (26.8) | |
| IV | 0 | 2 (0.7) |
Values are presented as number (%) or mean ± standard deviation.
PTMC, papillary thyroid microcarcinoma.