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. 2016 Jul 27;16:543. doi: 10.1186/s12885-016-2590-9

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Changes in body temperature and AFP. a After ten-day administration of sorafenib, the patient suffered from high fever from Mar. 29th, 2015. Upon cease of sorafenib use on Apr. 3rd, 2015, the high fever decreased quickly. After taking sorafenib again at Apr. 7th, and the fever developed. After daily administration of prednisone, the body temperature returned to the normal. b The serum AFP gradually dropped from 24793 ng/mL to 2.19 ng/mL from March 16th, 2015 to Apr. 12th, 2016