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. 2016 Jul 27;16:127. doi: 10.1186/s12886-016-0305-2

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — ICG angiogram with correlated OCT study in a previously treated eye in the PEARL 2 Study (12 2.0 mg ranibizumab + 12 1.0 mg ranibizumab) with additional bevacizumab intravitreal injections prior to entry into the EPIC study. a. Baseline EPIC Study images. ICG angiogram shows hypofluorescence (see arrowhead) in the area of the subretinal hyperreflective material and the central RPED. OCT shows a central RPED (arrow) with nasal subretinal hyperreflective material (asterisk). b. EPIC Month 6 imaging. ICG angiogram shows decrease in the area of hypofluorescence. OCT shows resolution of the subretinal hyperreflective material and decrease in the RPED. Visual acuity improved from 20/160 to 20/63 (+30 letters)