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(A) ChIP assay suggests that WRN may bind to the upstream promoter region of NHEJ1 in UM1 and UM2 oral cancer cells. Shown here is qPCR of the pull-down products from ChIP assays. (B) Co-IP assay suggests that mutant p53 binds to WRN in UM-SCC5 and UM-SCC10B cells. Western blotting was used to detect p53 in whole cell lysates, anti-WRN pull-down and negative control samples.
