Table 2.
Comparison of clinical variables and miRs in patients with NAFLD with and without cardiovascular disease
| NAFLD with CAD (N=32) | NAFLD without CAD (N=12) | p Value | |
|---|---|---|---|
| Age (years) | 64.22±8.23 | 57.92±11.74 | 0.14 |
| BMI (kg/m2) | 29.92±4.73 | 29.93±5.06 | 0.95 |
| WCC (103/μL) | 9.89±16.16 | 7.58±1.86 | 0.55 |
| Platelet (103/μL) | 207.31±42.93 | 238.83±56.73 | 0.07 |
| Glucose (mg/dL) | 133.27±95.05 | 146.75±88.95 | 0.25 |
| ALT (U/L) | 27.37±15.27 | 20.83±7.55 | 0.15 |
| AST (U/L) | 22.39±8.33 | 19.75±8.32 | 0.23 |
| Triglycerides (mg/dL) | 107.39±46.43 | 128.92±68.74 | 0.39 |
| LDL (mg/dL) | 80.31±29.63 | 82.45±25.34 | 0.70 |
| Total cholesterol (mg/dL) | 151.50±33.55 | 148.64±28.18 | 0.77 |
| HDL (mg/dL) | 44.52±15.10 | 40.50±13.87 | 0.45 |
| Gender (male) | 27 (84.4%) | 12 (100.0%) | 0.1458 |
| miR-132 | 0.24±0.16 | 0.30±0.11 | 0.039 |
| miR-143 | 0.96±0.90 | 0.64±0.77 | 0.028 |
p<0.05 is considered significant. Values are presented as mean and SD.
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; CAD, coronary artery disease; GGT, γ-glutamyl transferase; HDL, high-density lipoprotein; LDL, low-density lipoprotein; miR, microRNA; NAFLD, non-alcoholic fatty liver disease; WCC, white cell count.