Table 1.
Type 2 diabetes (T2D) drug responsiveness associated Single Nucleotide Polymorphisms (SNPs).
Chromosome | Position | Localization | Gene | Alleles | SNP ID | Amino Acid Change |
---|---|---|---|---|---|---|
6 | 160543148 | Exon | SLC22A1 | C/T | rs12208357 | R61C |
160560824 | Exon | A/G | rs34130495 | G401S | ||
160560881 | Exon | -/A | rs35167514 | 420del | ||
160575837 | Exon | A/C/G | rs34059508 | G465R | ||
6 | 160670282 | Exon | SLC22A2 | G/T | rs316019 | S270A |
11 | 17409572 | Exon | KCNJ11 | T/C | rs5219 | K23E |
17408630 | Exon | G/A | rs5215 | V337I | ||
10 | 114808902 | Intron | TCF7L2 | G/T | rs12255372 | - |
114758349 | Intron | C/T | rs7903146 | - | ||
10 | 96702047 | Exon | CYP2C9 | C/T | rs1799853 | R144C |
96741053 | Exon | A/C | rs1057910 | I359L | ||
11 | 17418477 | Exon | ABCC8 | G/T | rs757110 | A1369S |
3 | 12393125 | Exon | PPARG | C/G | rs1801282 | P12A |
2 | 227093745 | Intergenic | IRS1 | C/T | rs2943641 | - |
227660544 | Exon | G/A | rs1801278 | G971R | ||
2 | 241534293 | Intron | CAPN10 | Indel | rs3842570 | - |
241531174 | Intron | A/G | rs3792267 | - | ||
241542703 | Intron | C/T | rs5030952 | - |