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Tested anti IR–VIS effects of Polypodium leucotomos (PL) extract: (A) ultraviolet radiation (UV), visible light (VIS), and infrared radiation (IR) depth penetration in the skin; and (B) main PL effects reflect its capacity to decrease MMP-1 upregulation induced by cutaneous exposure to IR–VIS. Black arrows indicate increased/decreased effects due to IR–VIS.
