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. 2016 Jul 11;17(7):1102. doi: 10.3390/ijms17071102

Figure 4.

Figure 4

AQP1 inhibitor prevented BM-MSC-CM-mediated invasion of U2OS and SNU-398 cells. (A,B) Invasion assay was performed using a Boyden chamber pre-coated with matrigel. Tumor cells were seeded in the upper chamber whereas 1% FBS (negative control), 10% FBS (positive control) and BM-MSC-CM were added to the lower chamber as chemoattractants. Tumor cells were treated or not treated with AQP1 inhibitor TEA (100 µM). Results are expressed as means ± SD. * p < 0.001 and # p < 0.001. Scale bar = 600 µm.