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. 2016 Jul 13;17(7):1119. doi: 10.3390/ijms17071119

Figure 7.

Figure 7

Identified druggable cavity in hAQP4. Cavity identified in the hAQP4 crystal structure (PDB entry: 3GD8 [21]) by the FLAPsite algorithm. As shown in the zoomed panel, the sole cavity found is located in proximity of the extracellular loop A and close to residues D69, T62 and T56. Adapted from reference [96].