Table 1.

Compounds known to inhibit water permeability of AQP4 and to block Neuromyelitis Optica (NMO)-IgG binding.

Compound	Effect on AQP4	Reference
2-(Nicotinamido)-1,3,4-thiadiazole	Inhibition of water permeability	[36,37]
Sumatriptan	Inhibition of water permeability	[37]
Rizatriptan	Inhibition of water permeability	[37]
Acetazolamide	Inhibition of water permeability	[34]
Arbidol	Blockage of NMO-IgG binding	[38]
Berbamine	Blockage of NMO-IgG binding	[38]
Tamarixetin	Blockage of NMO-IgG binding	[38]