Table 1.
AQP Type | AQP Isoforms | Permeability to Water | Permeability to Small Solutes (i.e., Glycerol, Urea, Monocarboxylates) | Ability to Form OAPs in the Plasma Membrane |
---|---|---|---|---|
AQP1 | AQP1 | Yes | No | No |
AQP4 | AQP4a (M1) | Yes | No | Only together with AQP4c |
AQP4c (M23) | Yes | No | Yes | |
AQP4e | Yes | No | Only together with AQP4c | |
AQP4b | ? | No | N/A | |
AQP4d | ? | No | N/A | |
AQP4f | ? | No | N/A | |
AQP9 | AQP9 ~32 kDa (is AQP9 ~30 kDa its splicing isoform?) | Yes | Yes | No |
AQP9 ~25 kDa | Yes | Yes | No |
?, not yet definitely determined; N/A, not applicable; OAPs, orthogonal arrays of particles.