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Correlation between histopathological grade and chondrocyte apoptosis. (A) The TUNEL assay was performed to identify chondrocyte apoptosis at different stages of OA (scale bar: 100 μm). Arrows indicate apoptotic cells; (B) Apoptotic cells were counted in the superficial layer (SL) and middle layer (ML) in cartilage sections for quantification. Apoptosis is quantified as the percentage apoptotic cells with respect to the total cells counted.
