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. 2016 Jul 20;17(7):1169. doi: 10.3390/ijms17071169

Figure 1.

Figure 1

Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and PD-1/L1 checkpoint blockade. MHC, major histocompatibility complex; TCR, T cell receptor; PD-1, programmed cell death-1; PD-L1, programmed cell death ligand-1; +, B7 receptor expressed; −, B7 receptor not expressed.