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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Placenta. 2016 Jun 11;44:61–68. doi: 10.1016/j.placenta.2016.06.004

Figure 1.

Figure 1

BaP induces PTGS2 expression with no significant effect on PTGS1, PTGIS, or TBXAS1. (A) Real-time PCR demonstrates a statistically significant induction of PTGS2 mRNA in a dose-dependent manner (*p=0.02 in comparison to vehicle; ^p<0.001 in comparison to vehicle). (B) A representative western blot from one subject also demonstrates a BaP-mediated increase in PTGS2 protein expression. (C) Densitometric analysis of western blot results from all subjects confirms an induction of PTGS2 protein expression with BaP 10−6 M (#p=0.008 in comparison to vehicle) and a trend toward induction with BaP 10−8 M (p=0.06).