Table 2. Allele frequency and Hardy-Weinberg equilibrium of SNPs in TCF7L2.
| SNP | HapMap |
This study |
HWE P | |||||
|---|---|---|---|---|---|---|---|---|
| Genotype(%) | Major/minor Allele | MAF | Minor Allele | MAF | ||||
| rs10749127 | CC (0.374) | CT (0.475) | TT (0.151) | C/T | 0.389 | T | 0.30 | 0.62 |
| rs10787475 | TT (0.588) | TC (0.357) | CC (0.054) | T/C | 0.233 | C | 0.27 | 0.61 |
| rs11196224 | CC (0.347) | CT (0.484) | TT (0.168) | C/T | 0.411 | T | 0.31 | 0.70 |
| rs12775879 | TT (0.623) | TG (0.333) | GG (0.045) | T/G | 0.211 | G | 0.25 | 0.68 |
| rs17130188 | TT (0.460) | TC (0.437) | CC (0.104) | T/C | 0.322 | C | 0.43 | 0.20 |
| rs290481 | AA (0.430) | AG (0.451) | GG (0.118) | A/G | 0.344 | G | 0.35 | 0.94 |
| rs290487 | TT (0.412) | TC (0.456) | CC (0.124) | T/C | 0.352 | C | 0.28 | 0.85 |
| rs290489 | GG (0.412) | GA (0.456) | AA (0.124) | G/A | 0.352 | A | 0.34 | 0.94 |
| rs3750804 | CC (0.387) | CT (0.470) | TT (0.143) | C/T | 0.378 | T | 0.23 | 0.79 |
| rs4918792 | GG (0.347) | GA (0.484) | AA (0.169) | G/A | 0.411 | A | 0.48 | 0.90 |
| rs6585194 | CC (0.334) | CG (0.488) | GG (0.178) | C/G | 0.422 | G | 0.33 | 0.74 |
| rs7085532 | AA (0.334) | AG (0.488) | GG (0.178) | A/G | 0.422 | A | 0.40 | 0.58 |
| rs7094463 | AA (0.262) | AG (0.500) | GG (0.238) | A/G | 0.488 | G | 0.44 | 0.83 |
| rs7919409 | TT (0.554) | TC (0.380) | CC (0.066) | T/C | 0.256 | C | 0.35 | 0.10 |
| rs966227 | CC (0.250) | CT (0.500) | TT (0.250) | C/T | 0.500 | T | 0.34 | 0.80 |
| rs7903146 | CC (0.956) | CT (0.043) | TT (0.001) | C/T | 0.022 | T | 0.02 | 0.93 |
| rs11196205 | GG (0.935) | GC (0.064) | CC (0.001) | G/C | 0.033 | C | 0.03 | 0.95 |
| rs12255372 | GG (0.978) | GT (0.022) | TT (0.000) | G/T | 0.011 | T | 0.01 | 0.89 |
MAF, Minor allele frequency; HWE, Hardy-Weinberg equilibrium; SNP, single-nucleotide polymorphism.