Table 5. Univariate and multivariate logistic regression analysis of risk factors associated with GDM.
| Factor | Univariate |
Multivariate |
||
|---|---|---|---|---|
| p value | Odds ratio (95% CI) | p value | Odds ratio (95% CI) | |
| Age >25 years (0 = no, 1 = yes) | 0.049 | 1.289 (1.006, 1.652) | 0.012 | 1.780 (1.391, 2.277) |
| Pre-BMI > 24 kg/m2 (0 = no, 1 = yes) | 0.003 | 1.456 (1.138, 1.865) | 0.018 | 1.592 (1.248, 2.531) |
| LDL-C level > 3.6 mmol/l (0 = no, 1 = yes) | <0.001 | 1.780 (1.391, 2.277) | 0.009 | 2.034 (1.561, 3.239) |
| SBP > 140 mmHg (0 = no, 1 = yes) | 0.074 | 1.884 (0.980, 3.469) | ||
| DBP > 90 mmHg (0 = no, 1 = yes) | 0.162 | 1.527 (0.840, 2.775) | ||
| rs290487 genotype (0 = TT, 1 = TC, 2 = CC) | 0.001 | 4.735(2.957, 7.584) | 2.686 (1.979, 4.372) | |
| rs6585194 genotype (0 = CC, 1 = CC, 2 = GG) | 0.027 | 0.628(0.4141, 0.951) | ||
| rs7094463 genotype (0 = AA, 1 = GA, 2 = GG) | <0.001 | 0.335(0.228, 0.491) | 0.005 | 0.429 (0.329, 0.559) |
Pre-BMI, body mass index of mothers before pregnancy; LDL-C, low-density lipoprotein cholesterol; SBP, systemic blood pressure; DBP, diastolic blood pressure; 95% CI, 95% confidence interval.