Table 5. Association results of the above 6 BMD associated loci from Table 4 with osteoporotic fractures.
| SNP | Gene | A1/A2 | MAF cases | MAF controls | OR (95%CI) | P |
|---|---|---|---|---|---|---|
| rs7124442 | BDNF | C/T | 0.062 | 0.089 | 0.67 (0.45–1.00) | 0.042 |
| rs11030119 | BDNF | T/C | 0.037 | 0.062 | 0.58 (0.35–0.96) | 0.024 |
| rs2938780 | PDE4D | C/T | 0.170 | 0.194 | 0.85 (0.65–1.11) | 0.238 |
| rs895526 | SATB2 | A/G | 0.497 | 0.491 | 1.02 (0.83–1.26) | 0.825 |
| rs2963826 | PDE4D | T/C | 0.171 | 0.194 | 0.86 (0.65–1.13) | 0.268 |
| rs6704641 | SATB2 | G/A | 0.500 | 0.489 | 1.04 (0.85–1.29) | 0.658 |
Note: MAF: minor allele frequency for the A1 (minor allele); OR: odds ratio; CI: confidence interval.