Table 1.
United States: Antigenic match between seasonal trivalent influenza vaccine strains and circulating influenza viruses from 2000-01 to 2014-15.*7,8
|
TIV composition: northern hemisphere5 |
Circulating viruses: United States |
||||||||
|---|---|---|---|---|---|---|---|---|---|
|
% of all positive specimens |
% of Type A (with subtyping performed)predominant strain (with characterisation performed) |
% of Type B lineagespredominant strain (with characterisation performed) |
|||||||
| Season | A(H1N1) | A(H3N2) | Type B | A | B | A/H1N1 | A/H3N2 | Yamagata | Victoria |
| 2014-15 | A/California/7/2009pdm09 | A/Texas/50/2012 | B/Massachusetts/2/2012 (YAM)† | 83.5% | 16.5% | 0.4% | 99.6% | 71.9% | 28.1% |
| (week 20) | A/California/7/2009 (100%) | A/Switzerland/9715293/201 (predominant) | B/Massachusetts/2/2012 (98.1%) | B/Brisbane/60/2008 (97.8%) | |||||
| A/Texas/50/2012 (18.6%) | |||||||||
| 2013-14 | A/California/7/2009pdm09 | A/Texas/50/2012 | B/Massachusetts/2/2012 (YAM)† | 87.4% | 12.6% | 90.3% | 9.7% | 72.9% | 27.1% |
| A/California/7/2009 (99.9%) | A/Texas/50/2012 (95.3%) | B/Massachusetts/2/2012 (99.0%) | B/Brisbane/60/2008 (100%) | ||||||
| 2012-13 | A/California/7/2009pdm09 | A/Victoria/361/2011 | B/Wisconsin/1/2010 (YAM) | 70.0% | 30.0% | 6.0% | 94.0% | 63.8% | 36.2% |
| A/California/7/2009 (98.7%) | A/Victoria/361/2011 (99.6%) | B/Wisconsin/1/2010 (100%) | Not specified | ||||||
| 2011-12 | A/California/7/2009 | A/Perth/16/2009 | B/Brisbane/60/2008 (VIC) | 82.0% | 18.0% | 25.0% | 73.0% | 48.0% | 52.0% |
| A/California/7/2009 (96.0%) | A/Perth/16/2009 (75.0%) | B/Wisconsin/01/2010 (100%) | B/Brisbane/60/2008 (95.0%) | ||||||
| A/Victoria/361/2011 (3.0%) | |||||||||
| 2010-11 | A/California/7/2009 | A/Perth/16/2009 | B/Brisbane/60/2008 (VIC) | 74.0% | 26.0% | 38.0% | 62.0% | 5.8% | 94.0% |
| A/California/7/2009 (99.8%) | A/Perth/16/2009 (96.8%) | Not specified | B/Brisbane/60/2008 (99.9%) | ||||||
| 2009-10 | A/Brisbane/59/2007 | A/Brisbane/10/2007 | B/Brisbane/60/2008 (VIC) | 99.0% | 1.0% | 95.0% | 4.0% | 11.6% | 88.4% |
| A/California/7/2009 (99.5%) | A/Perth/16/2009 (100%) | Not specified | B/Brisbane/60/2008 (100%) | ||||||
| 2008-09 | A/Brisbane/59/2007 | A/Brisbane/10/2007 | B/Florida/4/2006 (YAM) | 66.0% | 34.0% | 87.0% | 13.0% | 17.0% | 83.0% |
| A/Brisbane/59/2007 (100%) | A/Brisbane/10/2007 (100%) | B/Florida/04/2006 (100%) | Not specified | ||||||
| 2007-08 | A/Solomon Islands/3/2006 | A/Wisconsin/67/2005 | B/Malaysia/2506/2004 (VIC) | 71.0% | 29.0% | 26.0% | 74.0% | 98.0% | 2.0% |
| A/Solomon Islands/3/2006 (66.0%) | A/Brisbane/10/2007 (60.0%) A/Wisconsin/67/2005 (23.0%) | B/Florida/4/2006 (89.0%) | B/Ohio/01/2005** (75.0%) | ||||||
| A/Brisbane/59/2007 (29.0%) | |||||||||
| 2006-07 | A/New Caledonia/20/99 | A/Wisconsin/67/2005 | B/Malaysia/2506/2004 (VIC) | 79.2% | 20.8% | 62.3% | 37.7% | 23.0% | 77.0% |
| A/New Caledonia/20/99 (90.0%) | A/Wisconsin/67/2005 (24.0%) | Not specified | B/Ohio/01/2005** (50.0%) | ||||||
| 2005-06 | A/New Caledonia/20/99 | A/California/7/2004 | B/Shanghai/361/2002 (YAM) | 79.7% | 20.3% | 8.1% | 91.9% | 18.7% | 81.3% |
| A/New Caledonia/20/99 (97.0%) | A/California/07/2004 (72.8%) A/Wisconsin/67/2005 | B/Florida/07/2004 (81.7%)B/Shanghai/361/2002 (16.7%) | B/Ohio/1/2005 (99.9%) | ||||||
| 2004-05 | A/New Caledonia/20/99 | A/Fujian/411/2002 | B/Shanghai/361/2002 (YAM) | 75.4% | 24.6% | 0.3% | 99.7% | 74.4% | 25.6% |
| A/New Caledonia/20/99 (100%) | A/California/7/2004 (78.0%) A/Wyoming/3/2003** (22.0%) | B/Shanghai/361/2002 (83.0%) | Not specified | ||||||
| 2003-04 | A/New Caledonia/20/99 | A/Moscow/10/99 | B/HongKong/330/2001 (VIC) | 99.0% | 1.0% | 0.1% | 99.9% | 93.0% | 7.0% |
| Not specified | A/Fujian/411/2002 (H3N2) (88.8%) | B/Sichuan/379/99 (100%) | B/Hong Kong/330/2001 (100%) | ||||||
| A/Panama/2007/99** (11.2%) | |||||||||
| 2002-03 | A/New Caledonia/20/99 | A/Moscow/10/99 | B/HongKong/330/2001 (VIC) | 56.4% | 43.6% | 70.3% | 29.7% | 0.4% | 99.6% |
| A/New Caledonia/20/99 (100%) | A/Panama/2007/99** (85.0%) | B/Shizuoka/15/2001 | B/Hong Kong/330/01 | ||||||
| 2001-02 | A/New Caledonia/20/99 | A/Moscow/10/99 | B/Sichuan/379/99 (YAM) | 87.5% | 12.5% | 1.9% | 98.1% | 22.8% | 77.2% |
| A/New Caledonia/20/99 (100%) | A/Panama/2007/99** (100%) | B/Sichuan/379/99 (21.3%) | Not specified | ||||||
| B/Shizuoka/15/2001 (predominant) | |||||||||
| 2000-01 | A/New Caledonia/20/99 | A/Moscow/10/99 | B/Beijing/184/93 (YAM) | 54.0% | 46.0% | 97.0% | 3.0% | 100% | |
| A/New Caledonia/20/99 (95.0%) | A/Panama/2007/99** (100%) | B/Beijing/184/93 (11.0%) | |||||||
| A/Bayern/07/95 (5.0%) | B/Sichuan/379/99** (89.0%) | ||||||||
* For influenza A, mismatch accounting for at least 40% of A-viruses antigenically characterised are indicated in yellow shading. For influenza B, co-circulation or mismatch accounting for at least 40% of B-viruses antigenically characterised are indicated in dark shading
**Viruses characterised that were antigenically similar to the strains specified by the WHO, for example A/Panama/2007/99 is an A/Moscow/10/99 (H3N2)-like virus.
†As from 2013-14 WHO recommends that quadrivalent seasonal influenza vaccines contain a second influenza B virus strain: in 2013-14 and 2014-15 this was a B/Brisbane/60/2008-like virus (VIC)
YAM = Yamagata lineage, VIC = Victoria lineage.