Table 3.
Europe: Antigenic match between seasonal trivalent influenza vaccine strains and circulating influenza viruses from 2000-01 to 2014-15.*11
| TIV composition: northern hemisphere 5 |
Circulating viruses: Europe |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| A(H1N1) |
A(H3N2) |
Type B |
% of all positive specimens |
% of Type A (with subtyping performed) predominant strain (with characterisation performed) |
% of Type B lineages predominant strain (with characterisation performed) |
||||
| Season | A | B | A/H1N1 | A/H3N2 | Yamagata | Victoria | |||
| 2014-15 | A/California/7/2009pdm09 | A/Texas/50/2012 | B/Massachusetts/2/2012 (YAM)† | 67% | 33% | 23.1% | 76.9% | 97.7% | 2.3% |
| (week 20) | A/California/07/2009 | A/Switzerland/9715293/2013 (71.0% of H3) | B/Massachusetts/02/2012 (19.9% of YAM) | B/Brisbane/60/2008 (100% of VIC) | |||||
| A/Texas/50/2012 (29.0% of H3) | B/Phuket/3073/2013 (79.2% of YAM) B/Wisconsin/1/2010 (0.1% of YAM) | ||||||||
| B/Florida/4/2006 (0.7% of YAM) | |||||||||
| 2013-14 | A/California/7/2009pdm09 | A/Texas/50/2012 | B/Massachusetts/2/2012 (YAM)† | 98% | 2% | A/California/07/2009 | A/Texas/50/2012 | 69.5% | 30.5% |
| (60.0% of all) | (37.0% of all) | B/Wisconsin/1/2010(12.2% of YAM) | B/Brisbane/60/2008(100% of VIC) | ||||||
| B/Massachusetts/02/2012 (85.4% of YAM) | |||||||||
| 2012-13 | A/California/7/2009pdm09 | A/Victoria/361/2011 | B/Wisconsin/1/2010 (YAM) | 48.5% | 51.5% | 58.0% | 42.0% | 86.0% | 14.0% |
| A/California/07/2009 | A/Victoria/361/2011 | B/Wisconsin/1/2010 (25.0% of all) | B/Brisbane/60/2008 | ||||||
| (9.5% of all) | (55.0% of all) | B/Florida/4/2006 (0.5% of all) | (6.6% of all) | ||||||
| 2011-12 | A/California/7/2009 | A/Perth/16/2009 | B/Brisbane/60/2008 (VIC) | 89.3% | 10.7% | 1.5% | 98.5% | 39.6% | 60.4% |
| A/California/07/2009 | A/Perth/16/2009 (74.3%) | not specified | not specified | ||||||
| (58.1% of A/H3 viruses had an imperfect genetic match with vaccine strain) | |||||||||
| 2010-11 | A/California/7/2009 | A/Perth/16/2009 | B/Brisbane/60/2008 (VIC) | 59.6% | 40.4% | 97.0% | 3.0% | <10% | B/Brisbane/60/20089 |
| A/California/07/2009 | A/Perth/16/2009 | B/Florida/4/2006 | (Predominant) | ||||||
| B/Bangladesh/3333/2007 | |||||||||
| 2009-10 | A/Brisbane/59/2007 | A/Brisbane/10/2007 | B/Brisbane/60/2008 (VIC) | 99% | 1% | A/California/07/2009 (99.7% of all) | <0.1% of all | Not specified | Not specified |
| 2008-09 | A/Brisbane/59/2007 | A/Brisbane/10/2007 | B/Florida/4/2006 (YAM) | 81.4% | 18.6% | A/Brisbane/59/2007 (3.7% of all) | A/Brisbane/10/2007 (37.1% of all) | B/Florida/4/2006 (0.8% of all) | B/Malaysia/2506/2004 (20.7% of all) |
| B/Brisbane/60/2008 (1.6% of all) | |||||||||
| 2007-08 | A/Solomon Islands/3/2006 | A/Wisconsin/67/2005 | B/Malaysia/2506/2004 (VIC) | 60% | 40% | A/Solomon Islands/3/2006 (58.0% of all) | A/Brisbane/10/2007 (1.5% of all) | B/Florida/4/2006 predominant (38.0% of all) | B/Malaysia/2506/2004 (0.5% of all) |
| A/New Caledonia/20/99 (1.5% of all) | A/Wisconsin/67/2005 (0.8% of all) | ||||||||
| 2006-07 | A/New Caledonia/20/99 | A/Wisconsin/67/2005 | B/Malaysia/2506/2004 (VIC) | 97.2% | 2.8% | 10.7% | 89.3% | B/Jiangsu/10/2003 (1.0% of all) | B/Malaysia/2506/2004 (4.0% of all) |
| A/New Caledonia/20/99 (8.0% of all) | A/Wisconsin/67/2005 (86.0% of all) | ||||||||
| A/California/7/2004 (1.0% of all) | |||||||||
| 2005-06 | A/New Caledonia/20/99 | A/California/7/2004 | B/Shanghai/361/2002 (YAM) | 42.0% | 58.0% | 48.0% | 51.8% | Not specified | Not specified |
| Not specified | Not specified | ||||||||
| 2004-05 | A/New Caledonia/20/99 | A/Fujian/411/2002 | B/Shanghai/361/2002 (YAM) | 83.3% | 16.7% | 18.2% | 81.8% | Not specified | 43.0% |
| Not specified | A/Wellington/1/2004 | B/Hong Kong/330/2001 | |||||||
| A/California/7/2004 | |||||||||
| 2003-04 | A/New Caledonia/20/99 | A/Moscow/10/99 | B/HongKong/330/2001 (VIC) | 99.1% | 0.9% | 0.5% | 99.1% | Not specified | Not specified |
| Not specified | Not specified | ||||||||
| 2002-03 | A/New Caledonia/20/99 | A/Moscow/10/99 | B/HongKong/330/2001 (VIC) | 63.4% | 36.4% | 9.7% | 88.8% | Not specified | Not specified |
| Not specified | Not specified | ||||||||
| 2001-02 | A/New Caledonia/20/99 | A/Moscow/10/99 | B/Sichuan/379/99 (YAM) | 74.9% | 25.1% | 3.8% | 87.3% | Not specified | Not specified |
| Not specified | Not specified | ||||||||
| 2000-01 | A/New Caledonia/20/99 | A/Moscow/10/99 | B/Beijing/184/93 (YAM) | 70.3% | 29.7% | 96.7% | 3.1% | Not specified | Not specified |
| Not specified | Not specified | ||||||||
* For influenza A, mismatch accounting for at least 40% of A-viruses antigenically characterised are indicated in yellow shading. For influenza B, co-circulation or mismatch accounting for at least 40% of B-viruses antigenically characterised are indicated in dark shading
†As from 2013-14 WHO recommends that quadrivalent seasonal influenza vaccines contain a second influenza B virus strain: in 2013-14 and 2014-15 this was a B/Brisbane/60/2008-like virus (VIC)
YAM = Yamagata lineage, VIC = Victoria lineage.
(X% of all) = percentage of all viruses (A +B) that were antigenically subtyped
% of A/B etc = percentage of all viruses subtyped as ‘A’ or ‘B’ etc
Note that numbers were derived from EU reports which summarise data from the different EU countries in which the virus circulation was not always perfectly homogenous.