Table 2.
Multivariate analysis of clinical and pathologic variables associated with disease-specific survival (DSS) and distant recurrence-free survival (DRFS) for the entire cohort and for the subset with myxofibrosarcoma.
| Variable | DSS | DRFS | ||
|---|---|---|---|---|
|
| ||||
| Multivariate HR (95% CI) | p-value | Multivariate HR (95% CI) | p-value | |
| Myxofibrosarcoma and UPS (n=197) | ||||
| % Myxoid component (<5% vs. ≥5%) | 2.1 (1.4–3.2) | 0.001 | 2.5 (1.7–3.8) | <0.001 |
| Size (≥10 cm vs. <10 cm) | 2.2 (1.4–3.4) | <0.001 | 2.2 (1.4–3.2) | <0.001 |
| Age (≥65 vs. <65) | 1.6 (1.1–2.5) | 0.025 | 1.1 (0.7–1.6) | 0.73 |
|
| ||||
| Myxofibrosarcoma only (n=128) | ||||
| % Myxoid component (<70% vs. ≥70%) | 2.1 (1.2–3.9) | 0.015 | 2.7 (1.5–4.8) | 0.001 |
| Size (continuous) | 1.11 (1.05–1.16) | <0.001 | 1.12 (1.07–1.17) | <0.001 |
HR, hazard ratio