Table 2.
Antibody response to RSV during the study period among 35 RSV-positive patients.
| GMT at V1 (SD), log2 units | GMT at V2 (SD), log2 units | GMT fold change, log2 units | 95% CI of fold change, log2 units | p-value | |
|---|---|---|---|---|---|
| Birth date | |||||
| < 7 months | 7.1 (1.5) | 7.9 (1.1) | 0.8 | (−0.2, 1.9) | Ref. |
| ≥ 7 months | 5.3 (1.4) | 9.2 (1.0) | 3.9 | (3.1, 4.6) | <0.001 |
| Virus type | |||||
| RSV A | 5.7 (1.6) | 8.8 (1.2) | 3.1 | (2.3, 4.0) | Ref. |
| RSV B | 6.9 (1.5) | 8.5 (1.1) | 1.7 | (−0.1, 3.4) | 0.15 |
| Viral load | |||||
| < 16 (copies/mL) | 6.5 (1.8) | 8.8 (1.3) | 2.2 | (1.2, 3.3) | Ref. |
| ≥ 16(copies/mL) | 5.3 (1.3) | 8.8 (1.1) | 3.5 | (2.5, 4.6) | 0.11 |
| Viral shedding | |||||
| <15 days | 5.6 (1.8) | 8.6 (1.2) | 3.0 | (1.9, 4.1) | Ref. |
| ≥15 days | 6.2 (1.5) | 8.9 (1.2) | 2.7 | (1.5, 3.8) | 0.70 |
| Symptoms | |||||
| URTIs | 6.3 (1.7) | 9.1 (1.0) | 2.7 | (1.6, 3.9) | Ref. |
| LRTIs | 5.5 (1.5) | 8.5 (1.3) | 3.0 | (1.9, 4.1) | 0.76 |
95% CI, 95% confidence interval; GMT, geometric mean titres; LRTIs, lower respiratory tract infections; RSV, respiratory syncytial virus; URTIs, upper respiratory tract infections.