Table 4.
Duration of shedding among 35 RSV-positive patients.
| Variable | Median shedding duration in days (95% CI) | HRa | 95% CIa | p-valuea | Adjusted HRb | 95% CIb | p-valueb |
|---|---|---|---|---|---|---|---|
| Birth date | |||||||
| < 7 months | 14 (13, 21) | Ref. | |||||
| ≥ 7 months | 28 (15, 50) | 2.3 | (1.0, 5.3) | 0.06 | |||
| Virus type | |||||||
| RSV A | 15 (14, 28) | Ref. | Ref. | ||||
| RSV B | 19 ( 7, 42) | 1.1 | (0.4, 2.8) | 0.82 | 0.8 | (0.3, 2.1) | 0.66 |
| Viral load | |||||||
| < 16 (copies/mL) | 14 (9, 21) | Ref. | Ref. | ||||
| ≥ 16(copies/mL) | 27 (14, 42) | 0.5 | (0.2, 1.0) | 0.05 | 0.4 | (0.2, 0.9) | 0.03 |
| Symptoms | |||||||
| URTI | 14 ( 9, 28) | Ref. | Ref. | ||||
| LRTI | 21 (14,35) | 0.7 | (0.3, 1.3) | 0.23 | 0.4 | (0.2, 0.9) | 0.03 |
| Antibody titer increase between V1 and V2 | |||||||
| <4-fold | 15 ( 9, 35) | Ref. | Ref. | ||||
| ≥4 -fold | 16 (14, 28) | 1.1 | (0.5, 2.3) | 0.84 | 0.7 | (0.3, 1.6) | 0.41 |
95% CI, 95% confidence interval; GMT, geometric mean titres; LRTIs, lower respiratory tract infections; RSV, respiratory syncytial virus; URTIs, upper respiratory tract infections.
a
In columns 3, 4, and 5, the HRs of the shedding duration between the 2 modalities of the variable of interest and the corresponding 95% CI and p-value are obtained by a simple Cox regression model.
b
In columns 6, 7, and 8, the adjusted HRs of the shedding duration between the 2 modalities of the variable of interest and the corresponding 95% CI and p-value are obtained by a multiple Cox regression model including birth date as an adjusting factor.