Table 3. Comparison of AMA Detection Methods.
Methods | Sensitivity | Specificity | Remarks |
---|---|---|---|
| |||
Immunofluorescence | 43.8-100% | 83.3-100% | [75,76,106] |
| |||
ELISA: | 72.9-100% | 76.5-100% | [106] |
Purified PDC | 83.8% | 98.8% | [76] |
MIT3 | 91.3% | 98.8% | [76] |
M2-3E* | 93.6% | 98.8% | [76] |
Cloned proteins from humans | 94.0% | 100% | [78] |
| |||
Immunoblotting | 85.0-94.9% | 84.8-100% | [106] |
| |||
Enzyme inhibition | 72-100% | 100% | [83-85] |
M2-3E is a mixture of purified PDC and MIT3 containing a combination of three E2-subunits.