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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Expert Rev Mol Diagn. 2016 Mar 30;16(6):697–705. doi: 10.1586/14737159.2016.1164038

Table 3. Comparison of AMA Detection Methods.

Methods Sensitivity Specificity Remarks

Immunofluorescence 43.8-100% 83.3-100% [75,76,106]

ELISA: 72.9-100% 76.5-100% [106]
Purified PDC 83.8% 98.8% [76]
MIT3 91.3% 98.8% [76]
M2-3E* 93.6% 98.8% [76]
Cloned proteins from humans 94.0% 100% [78]

Immunoblotting 85.0-94.9% 84.8-100% [106]

Enzyme inhibition 72-100% 100% [83-85]
*

M2-3E is a mixture of purified PDC and MIT3 containing a combination of three E2-subunits.