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. Author manuscript; available in PMC: 2016 Jul 28.
Published in final edited form as: Lancet. 2010 Dec 13;376(9758):2086–2095. doi: 10.1016/S0140-6736(10)61508-5

Table 5. Impact of intervention on severity of symptoms (mean CIS-R score) at 6 months, by facility type and diagnostic group at baseline (secondary analyses).

Diagnostic group at baseline Type of facility
p-value for effect modification
All facilities PHC GPs
ICD-10 cases (n=1961)
  Collaborative Stepped Care 9.30 9.28 9.32
  Enhanced Usual Care 11.61 14.12 9.10
  Mean difference (95% CI) -2.14 (-4.32, 0.04) -4.84 (-8.48, -1.20) 0.63 (-2.76, 4.02) .001
  P-value 0.05 0.02 0.68

Depression cases (n=673)
  Collaborative Stepped Care 11.38 11.30 11.47
  Enhanced Usual Care 12.54 15.60 9.48
  Mean difference (95% CI) -1.01 (-3.63, 1.61) -4.30 (-9.58, 0.98) 2.38 (-1.29, 6.05) <0.001
  P-value 0.42 0.09 0.17

Screen positive cases (n=2429)
  Collaborative Stepped Care 8.56 8.39 8.72
  Enhanced Usual Care 10.87 13.13 8.60
  Mean difference (95% CI) -2.15 (-4.20, -0.10) -4.75 (-8.86, -0.64) 0.52 (-2.36, 3.40) 0.001
  P-value 0.04 0.03 0.69

Sub-threshold cases (n=468)
  Collaborative Stepped Care 5.62 5.69 5.56
  Enhanced Usual Care 7.62 8.56 6.68
  Mean difference (95% CI) -1.90 (-4.01, 0.20) -2.87 (-8.09, 2.34) -0.91 (-3.25, 1.44) 0.20
  P-value 0.07 0.20 0.40