Table 1. Differences in mean and maximum SBP on home, ambulatory and premorbid readings, in patients with different degrees of cognitive impairment defined by MMSE versus MOCA.
Differences across levels of impairment are compared by ANOVA, with post-hoc comparisons between no impairment and significant impairment, with and without adjustment for age and gender. *p<0.05, **p<0.01, ***p<0.001.
Degree of cognitive impairment | Unadjusted | Adjusted | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Significant | Mild | None | ANOVA p-val | None vs Sig | ANOVA p-val | None vs Sig | ||||
HBPM | ||||||||||
Mean | ||||||||||
MOCA | 129.9 | (125.9 - 133.9) | 124.6 | (122.7 - 126.6) | 121.7 | (120.2 - 123.2) | <0.001*** | <0.001*** | <0.001*** | <0.001*** |
MMSE | 127.3 | (122.8 - 131.7) | 125 | (122.4 - 127.7) | 123 | (121.6 - 124.4) | 0.12 | 0.19 | 0.38 | 0.27 |
Maximum | ||||||||||
MOCA | 159.3 | (153.3 - 165.3) | 153.6 | (150.6 - 156.5) | 148.2 | (145.9 - 150.6) | <0.001* | <0.001* | 0.044* | 0.017* |
MMSE | 156.5 | (148.7 - 164.3) | 153.6 | (149.7 - 157.6) | 150.3 | (148.2 - 152.5) | 0.12 | 0.22 | 0.74 | 0.61 |
ABPM | ||||||||||
Mean | ||||||||||
MOCA | 131.4 | (127.2 - 135.7) | 126.9 | (124.7 - 129.1) | 126.5 | (125.1 - 127.9) | 0.028* | 0.022* | 0.009** | 0.002** |
MMSE | 128.5 | (123.1 - 133.9) | 127 | (124.4 - 129.7) | 127.3 | (125.9 - 128.6) | 0.87 | 0.88 | 0.8 | 0.5 |
Maximum | ||||||||||
MOCA | 168.4 | (161.9 - 174.8) | 162.6 | (159.3 - 165.9) | 160.8 | (158.2 - 163.4) | 0.045* | 0.035* | 0.15 | 0.17 |
MMSE | 165.5 | (155.5 - 175.5) | 162.6 | (158.3 - 166.9) | 161.9 | (159.7 - 164.2) | 0.68 | 0.66 | 0.68 | 0.39 |
Premorbid | ||||||||||
Mean | ||||||||||
MOCA | 143.4 | (140.3 - 146.5) | 140.2 | (138.2 - 142.2) | 135.3 | (133.4 - 137.1) | <0.001*** | <0.001**** | 0.018* | 0.01** |
MMSE | 138.9 | (134.6 - 143.2) | 141.8 | (139.5 – 144.1) | 136.7 | (135.2 - 138.3) | 0.007** | 0.68 | 0.05 | 0.58 |
Maximum | ||||||||||
MOCA | 170.9 | (164.9 - 176.9) | 164.5 | (161.1 - 167.9) | 155.9 | (153.0 – 158.96) | <0.001*** | <0.001*** | <0.001*** | <0.001*** |
MMSE | 162.9 | (155.4 – 170.4) | 168.0 | (163.5 – 172.6) | 158.5 | (155.9 – 161.0) | 0.002** | 0.56 | 0.02* | 0.61 |