Table 3. Risk of having a lower score on each subdivision of the MOCA and MMSE per 10mmHg increase in mean SBP.
Effect sizes are derived from ordinal regression for each cognitive subdomain, adjusted for age and gender. HBPM = home BP monitoring; ABPM = ambulatory BP monitoring; premorbid = up to the last 20 readings recorded in primary care.
MOCA | MMSE | |||||
---|---|---|---|---|---|---|
OR | CI | P-val | OR | CI | P-val | |
HBPM | ||||||
Visuo-Spatial | 1.24 | (1.08 - 1.42) | 0.002** | 1.29 | (1.07 - 1.56) | 0.009** |
Attention | 1.26 | (1.10 - 1.45) | <0.001*** | 1.09 | (0.95 - 1.26) | 0.20 |
Language | 1.18 | (1.03 - 1.35) | 0.015* | 1.17 | (0.92 - 1.49) | 0.20 |
Naming | 1.18 | (0.97 - 1.42) | 0.1 | 0.91 | (0.49 - 1.71) | 0.78 |
Recall | 1.13 | (1.00 - 1.29) | 0.06 | 1.06 | (0.92 - 1.22) | 0.41 |
Orientation | 1.14 | (0.96 - 1.36) | 0.14 | 1.13 | (0.96 - 1.33) | 0.13 |
Abstraction | 1.09 | (0.95 - 1.26) | 0.21 | - | ||
ABPM | ||||||
Visuo-Spatial | 1.08 | (0.94 - 1.25) | 0.29 | 1.04 | (0.84 - 1.29) | 0.71 |
Attention | 1.2 | (1.03 - 1.39) | 0.016* | 1.15 | (0.99 - 1.33) | 0.06 |
Language | 1.18 | (1.03 - 1.36) | 0.02* | 1.06 | (0.81 - 1.4) | 0.66 |
Naming | 1.25 | (1.02 - 1.52) | 0.033* | 0.89 | (0.45 - 1.79) | 0.75 |
Recall | 1.06 | (0.92 - 1.21) | 0.43 | 0.95 | (0.82 - 1.11) | 0.52 |
Orientation | 1.17 | (0.97 - 1.41) | 0.09 | 1.11 | (0.94 - 1.33) | 0.23 |
Abstraction | 1.03 | (0.88 - 1.19) | 0.75 | - | ||
Premorbid | ||||||
Visuo-Spatial | 1.29 | (1.12 - 1.48) | <0.001*** | 1.05 | (0.85 - 1.31) | 0.64 |
Attention | 1.18 | (1.02 - 1.36) | 0.025* | 1.07 | (0.92 - 1.24) | 0.38 |
Language | 1.22 | (1.06 - 1.41) | 0.005** | 0.91 | (0.69 - 1.2) | 0.5 |
Naming | 1.07 | (0.86 - 1.33) | 0.56 | 0.86 | (0.44 - 1.67) | 0.66 |
Recall | 1.06 | (0.93 - 1.21) | 0.4 | 1.07 | (0.93 - 1.25) | 0.34 |
Orientation | 0.92 | (0.76 - 1.12) | 0.4 | 0.96 | (0.81 - 1.15) | 0.69 |
Abstraction | 1.16 | (0.99 - 1.35) | 0.044* | - |