Table 1. List of the top hits of interactors identified by label-free quantitative mass spectrometry.
Gene name, description and total peptide count (TPC) is reported for each protein. *The same total peptide count was reported for the control (GST alone), see also Supplementary Table 1.
| Gene name | Iso1 (TPC) | Iso2 (TPC) | Iso3 (TPC) | |
|---|---|---|---|---|
| CLTC | clathrin, heavy chain (CHC) | 1050 | *153 | 1068 |
| SEC16A | SEC16 homolog A (S. cerevisiae) | 175 | 0 | 145 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 91 | 0 | 107 |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit | 87 | 0 | 89 |
| AP2A1 | adaptor-related protein complex 2, alpha 1 subunit | 85 | 0 | 90 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 28 | 0 | 32 |
| AP2M1 | AP-2 complex subunit mu | 35 | 0 | 51 |
| CLINT1 | clathrin interactor 1 (EPSIN4) | 138 | 0 | 146 |
| PIK3C2A | Class 2 phosphatidylinositol-4-phosphate 3-kinase | 73 | 0 | 90 |
| PICALM | Phosphatidylinositol-binding clathrin assembly protein | 15 | 0 | 19 |
| EPS15 | Epidermal growth factor receptor substrate 15 | 6 | 0 | 5 |
| REPS | RalBP1-associated Eps domain-containing protein 1 | 10 | 0 | 5 |
| COPB2 | Coatomer subunit beta' | 45 | 50 | 57 |
| DDB1 | DNA damage-binding protein 1 | 137 | 251 | 123 |
| EPRS | Bifunctional glutamate, proline, tRNA ligase | 206 | 686 | 183 |
| VPRBP | Vpr (HIV-1) binding protein (DCAF) | 0 | 140 | 0 |
| DCTN1 | dynactin 1 | 0 | 105 | 0 |
| GTPBP4 | GTP binding protein 4 | 5 | 44 | 0 |
| ARHGEF12 | Rho guanine nucleotide exchange factor 12 | 6 | 64 | 0 |
| YTHDC2 | Probable ATP-dependent RNA helicase | 4 | 37 | 2 |
| DCTN2 | Dynactin subunit 2 | 2 | 37 | 0 |
| DOCK7 | Dedicator of cytokinesis protein 7 | 2 | 32 | 4 |