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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: J Surg Res. 2016 Apr 22;204(1):47–54. doi: 10.1016/j.jss.2016.04.021

Figure 1. Indole-3-carbinol treatment activates the aryl hydrocarbon receptor in colorectal cancer cells.

Figure 1

Figure 1

A) DLD1, HCT116, HT-29, LS513, and RKO cells exhibited CYP1A1 mRNA upregulation following I3C treatment. With cell growth in logarithmic phase, cells were treated with either 500 μM I3C or 0.01% DMSO for 24 hours. Total RNA was harvested and reverse transcribed. Data are presented as relative fold induction of CYP1A1 mRNA of I3C treated cells over DMSO treated cells (controlled to internal levels of β-actin) ± standard error (representing at least three discrete experiments). “*” indicates statistical significance between I3C treated mRNA levels and vehicle (DMSO- μM) ) controls (p<0.05).