Table 1.

Compounds published before June 2008 grouped by assignee. Of each patent, a general structure and a representative compound are reported and the claimed core is highlighted in red*. Respective Protein Data Bank (PDB) identification codes are reported where available.

In all the reported structures R is any chemical group (hydrogen, aryl, alkyl, halogen etc); A and D are independently N, CH, S, O, NH and derivatives; J, X and Y are independently N and CH; Z is O, (un)substituted NH; W is N, O, S,:C(E1) or C(E1a); Ar is any 5 membered aromatic heterocycle; E is valence bond, CH₂, NH, O; F is valence bond, CH₂.