Table 2.

Compounds claimed in the analyzed patents grouped by assignee. A general structure and a representative compound are reported and the patented core is highlighted in red^*. Respective Protein Data Bank (PDB) identification codes are reported where available.

^*In all the reported structures R is any chemical group (aryl, alkyl, halogen etc); D, E, F and G are independently CH, N or NO; X is any heteroatom (NH, O, S etc); Y is independently N and C, provided that at least one Y is N; Z is independently N and C, provided that no more than two Z are N; J is O, S, N-cyclopropyl, NH, NEt, and NMe; W is O, (un)substituted CH2, NH; K C=(O) or SO2; L is a bond, A is any 3–7 membered, substituted or (un)substituted, aliphatic or aromatic ring; Q is CH or N; Ar is any aromatic ring. For a more detailed description of each chemical substituent we recommend to refer to the original patent application.