Table 1. Biological parameters in n = 18 mice longitudinally followed with spinal cord DTI.
Values are mean ± standard error of the mean (SEM).
| Spinal Cord IgG mRNA | TMEV Ab Serum | Rotarod Assay (190 dpi) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Group | # mice | Spinal Cord Viral load (copy number in 0.5 μg RNA) | Sham-Normalized Relative Expression | Day 24 | Day 108 | Day 190 | NFI | Sham Normalized NFI | Running time (sec) |
| TMEV-PCR Negative | 8 | 2.0±1.0 | 7.79±4.63 | 5.44x103 ±5.14x102 | 9.02x103 ±1.93x103 | 3.53x103 ±1.25x103 | 1.28±0.05 | 0.97±0.04 | 2.13x102 ±8.81 |
| TMEV-PCR Positive | 4 | 2.67x106 ±8.10x105 | 3.83x102 ±2.53x102 | 6.46x103 ±3.28x102 | 17.77x103 ±2.80x103 | 10.59x103 ±3.04x103 | 0.53±0.15 | 0.40±0.11 | 1.02x102 ±28.11 |
| Sham | 6 | 0±0 | / | 0±0 | 0±0 | 0±0 | 1.27±0.05 | / | 2.04x102 ±15.97 |