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Effects of HMGB1 blockade on serum levels of (A) high-mobility group box 1 (HMGB1), (B) tumor necrosis factor-α (TNF-α), and (C) interlukine-6 (IL-6) in the sham, ATC and ATCH (ATC with HMGB1 blockade) groups. Data are expressed as mean ±SD. * P<0.05, ATC versus ATCH; & P<0.05, ATC versus sham; # P<0.05, sham versus ATCH.
