Fig 7. Fructose and pyruvate metabolism.

Box and whisker plots of fructose, pyruvate, lactate and alanine in the prepubertal group. Given the tight correlation between these metabolites, we displayed the pyruvate metabolic pathway with its intermediates and enzymes. Enzyme 1, Fructokinase; 2, Aldolase B; 3, Glyceraldehyde kinase; 4, Triose phosphate isomerase; 5, further classic glycolytic enzymes; 6, Lactate dehydrogenase; 7, alanine transaminase. The FDR (q) is indicated for each metabolite. The significance of the post hoc comparison of the treatment groups to oil is indicated as follows: ** P < 0.01 or * P < 0.05.