Fig 1. Schematic representation of the BicMix biclustering model.

Ordered from left to right are, respectively, the p × n gene expression matrix Y, the p × K loading matrix Λ including both sparse and dense columns, the K × n factor matrix X including both sparse and dense rows, and the p × n residual matrix ϵ. Blue, red, and white entries in each matrix correspond to negative, positive, and zero values, respectively.