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(A) Representative ZR-75-1 tumors were imaged using PET/CT with 18F-FES on days 0, 3, 14, and 21 after treatment. The tumors are indicated by arrows. (B, C) 18F-FES PET/CT analysis (%ID/gmax and T/M) on days 0, 3, 14, and 21 after treatment. ** P< 0.001, within groups compared to baseline; # P< 0.05, ## P< 0.001 between treatment and vehicle groups.
