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. 2016 Jul 28;11(7):e0160042. doi: 10.1371/journal.pone.0160042

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© 2016 Li et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 6 — (A, B) TEM images of PGNPs internalized by H460 and H460_PTX cells. The figure is the representive of results from three independent expeiments. (C) Time-dependent cellular uptake of PGNPs by H460 and H460_PTX cells. Cells were treated with PGNPs at 2.5 nM for indicated times and cellular uptake of PGNPs was determined by ICP-MS. (D) Dose-dependent uptake of PGNPs by H460 and H460_PTX cells after treatment for 24 hrs. Each data point was measured in triplicate. Data are mean±s.d. *P<0.05, compared with that of H460 under the same treatment.