Table 4. Diversity and frequency of single-nucleotide polymorphisms displayed by Giardia duodenalis sub-assemblage BIV isolates at the glutamate dehydrogenase locus (partial sequence between positions 80 to 467) identified in the present study.
Nucleotide at position of reference sequence L40508 | |||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
87 | 105 | 123 | 135 | 183 | 186 | 201 | 228 | 231 | 255 | 258 | 273 | 282 | 291 | 295 | 300 | 327 | 336 | 345 | 366 | 372 | 387 | 396 | 423 | 432 | 438 | 450 | 462 | ||
C | C | C | T | T | G | G | C | G | C | C | C | G | C | G | C | C | T | C | T | C | T | C | C | C | A | A | T | ||
Sub-type | Number of isolates | ||||||||||||||||||||||||||||
KP899852 | 1 | T | . | . | C | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | C | T | C | . | . | . | G | . | . |
KP899853 | 1 | . | Y | Y | Y | . | . | . | . | . | Y | . | Y | . | . | . | . | . | . | . | . | . | C | . | . | . | . | . | . |
KP899854 | 1 | . | . | Y | . | Y | . | . | Y | . | . | . | . | . | . | . | . | . | . | Y | . | . | C | . | . | . | R | . | . |
KP899855 | 1 | . | . | . | Y | Y1 | R | . | . | . | Y | . | Y | . | . | . | . | . | . | . | Y | . | C | . | . | . | G | . | . |
KP899856 | 1 | . | . | . | Y | . | . | . | . | . | Y | . | Y | . | . | . | . | . | . | Y | Y | . | C | Y | . | . | R | . | . |
KP899857 | 1 | . | . | . | Y | . | . | . | . | . | . | . | T | . | . | . | . | . | . | Y | . | . | Y | . | . | . | R | . | . |
KP899858 | 1 | . | . | . | . | C | A | . | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
KP899859 | 1 | . | . | . | . | C | R | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | C | . | . | . | R | . | . |
KP899860 | 1 | . | . | . | . | C | . | A | . | A | . | . | . | . | . | . | . | . | . | . | . | . | C | T | . | . | . | . | . |
KP899861 | 1 | . | . | . | . | C | . | . | Y | . | Y | . | Y | . | . | . | . | Y | . | Y | C | Y | C | . | . | . | R | . | . |
KP899862 | 1 | . | . | . | . | Y | . | . | Y | . | Y | . | Y | . | . | . | . | Y | . | . | Y | . | C | . | . | . | . | . | . |
KP899863 | 1 | . | . | . | . | Y | . | . | Y | . | Y | . | Y | . | . | . | . | . | . | . | . | . | C | . | . | . | . | . | . |
KP899864 | 1 | . | . | . | . | Y | . | . | . | . | . | . | . | . | . | . | . | . | . | . | Y | . | C | . | . | . | R | . | . |
KP899865 | 1 | . | . | . | . | C | . | . | . | . | . | . | T | . | . | A2 | . | . | . | . | . | . | C | . | . | T | . | . | . |
KP899866 | 1 | . | . | . | . | Y | . | . | . | . | . | . | . | R | . | . | . | . | . | . | . | . | C | . | . | . | . | . | . |
KP899867 | 1 | . | . | . | . | C | . | . | . | . | . | . | . | . | . | . | Y | . | . | Y | Y | . | C | Y | Y | . | . | . | . |
KP899868 | 1 | . | . | . | . | Y | . | . | . | . | . | . | . | . | . | . | . | . | . | Y | Y | . | Y | Y | . | . | R | R | Y |
KP899869 | 2 | . | . | . | . | C | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | C | . | . | . | . | . | . |
KP899870 | 1 | . | . | . | . | C | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | C | Y | Y | . | R | . | . |
KP899871 | 1 | . | . | . | . | . | . | . | . | . | T | . | . | . | . | . | . | . | . | . | . | . | C | . | . | . | . | . | . |
KP899872 | 1 | . | . | . | . | . | . | . | . | . | . | Y | Y | . | S | . | . | . | . | . | . | . | C | . | . | . | R | . | . |
KP899873 | 1 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | C | . | C | . | . | . | G | . | . |
KP899874 | 1 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | Y | . | . | . | C | . | . | . | . | . | . |
R: A/G; S: G/C; Y: C/T.
1 p.M63X.
2 p.A99T.