Fig 5.

Cell-cycle analysis after treatment with two concentrations (a: 125 and b: 1000 mg/L) of Fr 1: total extract (1), Fr 2: vit. C (2), Fr 3: neutral polyphenols (3) and Fr 4: acid polyphenols or flavonoids (4) from rosehip (Rosa canina L) after 72 h. In control (C), the cells are without treatment. Cell cycle and DNA fragmentation were determined by propidium iodide staining. Percentages of G₁, S and G₂-phase are shown when possible. Experiments were performed in triplicate.