. Author manuscript; available in PMC: 2016 Jul 28.

Published in final edited form as: IEEE Trans Med Imaging. 2016 Feb 11;35(7):1729–1740. doi: 10.1109/TMI.2016.2527717

TABLE VI.

Spatial extent and estimates of group effect sizes and embedded nonlinearities of NICE components with differential GMC with RBM reduction to 30 dimensions. Underlined brain regions are those with negative component coefficients (reversed loadings directionality).

Comp Number	Loadings Directionality	Brain Regions	Input-Output Dependence Metrics			Effect size of loadings (Cohen’s d)
Comp Number	Loadings Directionality	Brain Regions	Max. Corr.	Max. Adj. MI	Linear fit (R²)	Linear	Back- reconstructed
1	Ct > Sz	Superior Temporal Gyrus Insula Caudate Nucleus Anterior Cingulum Thalamus	0.93	0.10	0.90	0.50	0.19
2	Ct > Sz	Superior Medial Frontal Gyrus Thalamus Vermis	0.92	0.12	0.84	0.53	0.50
3	Ct > Sz	Superior Occipital Gyrus Middle Occipital Gyrus Calcarine Sulcus	0.87	0.13	0.84	0.53	0.55
4	Ct > Sz	Superior Temporal Gyrus Middle Temporal Gyrus Left Middle Occipital Gyrus	0.98	0.08	0.97	0.51	0.02
5	Sz > Ct	Cerebellum Crus Vermis	0.96	0.12	0.92	−0.66	−0.52