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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Steroids. 2016 Mar 24;111:100–112. doi: 10.1016/j.steroids.2016.03.010

Fig. 1.

Fig. 1

Examples of actions of bath applied histamine (HA) and the rapid E2 effects on them. Each series of traces connected by dashed lines are segments of a continuous recording from a single neuron. Tetrodotoxin (TTX) (0.5 µM) was included in the bathing solution. Horizontal bars under each trace indicate the duration of HA application. The minutes in parentheses following HA+E2 indicate the duration of E2 application at the time of HA administration. The time above the dashed lines between traces indicates the gap duration. Acutely applied E2 potentiated HA-induced depolarization in series A, abolished hyperpolarization in series B, and converted hyperpolarization into depolarization in series C.