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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Steroids. 2016 Mar 24;111:100–112. doi: 10.1016/j.steroids.2016.03.010

Fig. 11.

Fig. 11

Rapid E2 potentiation of depolarizations induced by current injection and by NMDA. Same experimental procedure as that shown in Fig. 7, except that NMDA was used in place of HA. The results are qualitatively identical to those illustrated in Fig. 7. That is, NMDA, E2 alone and E2 together with NMDA caused successively greater potentiation of current injection induced depolarization that include: 1) shortening of latency; 2) increase in number of AP; 3) increase in relative depolarization; and 4) increase in depolarization rate. Measurements also revealed a lowering of AP threshold.