Skip to main content
. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Neurochem Res. 2016 May 25;41(9):2278–2288. doi: 10.1007/s11064-016-1942-9

Figure 3. Cleaved tau immunoreactivity and caspase activity in the cerebellum showed no difference between young and aged mice.

Figure 3

(a) Representative immunoblots from 10 animals for each group showing immunoreactivity for cleaved tau (CTau) and actin (loading control) in the cerebellum of young and aged mice. Each well number represents an individual animal. (b) Quantitative densitometry revealed no significant difference in cleaved tau levels in the cerebellum of young and aged mice. Tau density was normalized to actin. (c) Similarly, caspase activity, measured using the substrate DEVD-afc showed no significant difference (P=0.0775, R2=0.3060) in the cerebellum of aged mice compared to young. Caspase activity was normalized to buffer alone. Data are shown as mean+/−SEM. Green squares represent young individuals, blue triangles represent aged. n = 10 mice per group. Blots were confirmed in duplicate.